The various enzymes present in the secretions of GIT.
Enzyme Name |
Source |
Substrates |
Products |
Notes (if applicable) |
Aminopeptidase |
Small intestine |
Amino acid at
amino end of peptides |
Amino acids &
peptides |
n/a |
Carboxypeptidase |
Pancreatic acinar
cells |
Amino acid at
carboxyl end of peptides |
Amino acids &
peptides |
Activated from
procarboxypeptidase by trypsin; optimum pH varies |
Chymotrypsin |
Pancreatic acinar
cells |
Proteins |
Peptides |
Activated from
chymotrypsinogen by trypsin; optimum pH 7.8 |
Deoxyribonuclease |
Pancreatic acinar
cells |
DNA |
Nucleotides |
n/a |
Dipeptidase |
Small intestine |
Dipeptides |
Amino acids |
n/a |
Elastase |
Pancreatic acinar
cells |
Proteins |
Peptides |
Activated from
proelastase by trypsin |
Enterokinase |
Small intestine |
Trypsinogen |
Trypsin |
n/a |
Gastric lipase |
Stomach chief
cells |
Triglycerides |
Fatty acids &
monoglycerides |
Optimum pH 4-5 |
Lactase |
Small intestine |
Lactose |
Glucose &
galactose |
n/a |
Lingual lipase |
Lingual glands in
tongue |
Triglycerides
(fats & oils) & other lipids |
Fatty acids &
diglycerides |
Optimum pH
4.5-5.5 |
Maltase |
Small intestine |
Maltose |
Glucose |
n/a |
Nucleosidases & phosphatases |
Small intestine |
Nucleotides |
Nitrogenous
bases, pentoses, phosphates |
n/a |
Pancreatic amylase |
Pancreatic acinar
cells |
Starches |
Maltose,
maltotriose, α-dextrins |
Optimum pH
6.7-7.0 |
Pancreatic lipase |
Pancreatic acinar
cells |
Triglycerides
emulsified by bile salts |
Fatty acids &
monoglycerides |
Optimum pH 8.0 |
Pepsin |
Stomach chief
cells |
Proteins |
Peptides |
Activated from
pepsinogen by pepsin & HCl; optimum pH 1.5-1.6 |
Ribonuclease |
Pancreatic acinar
cells |
RNA |
Nucleotides |
n/a |
Sucrase |
Small intestine |
Sucrose |
Glucose &
fructose |
n/a |
Salivary amylase |
Salivary glands |
Starches |
Maltose,
maltotriose (trisaccharide), α-dextrins |
Optimum pH 6.7-7 |
Trypsin |
Pancreatic acinar
cells |
Proteins |
Peptides |
Activated from
trypsinogen by enterokinase; optimum pH 7.8-8.7 |
α-Dextrinase |
Small intestine |
α-dextrins |
Glucose |
n/a |
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